I have come across a problem when attempting to use MS Access on Windows 10 Enterprise 1809. This problem occurs whether I am opening Access directly or trying to open a file with the .accdb extension.

This is my first attempt to run Access on this particular computer. All other Office 365 programs, such as Word, Excel, PowerPoint, Outlook, Skype for Business, and even Visio, are functioning properly. I can also manually modify regedit.exe without any issues.

The version of Office 365 that I am using is 1902 (Build 11328.20368), which was initially deployed via SCCM, so all users in my workplace have the same version. Updating or downgrading to a different version is not a viable solution as I will be reverted back to this version quickly.

I have attempted several potential solutions, including restarting the computer, opening MS Access in safe mode, performing a quick or full online repair, manually uninstalling and reinstalling the program, removing Office and other related Microsoft products like InfoPath, SharePoint Designer 2010/2013, and similar non-Microsoft tools that may cause conflicts.

This is a new error for me, and internet search results are for older versions (circa 2010 or 2007) and suggest repairing or reinstalling the program if the repair fails.

The most recent cumulative update, except for KB4507419, was KB4512534, which is called “2019-08 Cumulative Update for Windows 10 Version 1809 for x64-based Systems.”

It is possible that the problem is related to my registry rather than Access. What steps should I take to resolve this issue and be able to open Access once again?

Askify Moderator Edited question April 30, 2023